New studies suggest that overloading the body with iron may be another way asbestos can trigger mesothelioma. And ridding the body of that excess iron may eventually be another way to help manage this cancer.
Malignant mesothelioma is caused by exposure to asbestos, especially crocidolite and amosite asbestos, whose tiny sharp fibers contain high amounts of iron. In recent years, medical researchers have confirmed that chronic inflammation caused by the irritation of asbestos fibers appears to be one of the triggers for mesothelioma. But mounting evidence suggests that the iron in asbestos may also play a role in this aggressive cancer.
While iron is essential for health, numerous epidemiological studies have shown it to be carcinogenic in high amounts. To test the connection between iron and mesothelioma, scientists repeatedly injected iron saccharate into the peritoneal cavity of lab rats. As predicted, many of the rats developed peritoneal mesothelioma.
When these mesothelioma cells were analyzed using an array-based comparative genomic hybridization (aCGH) and gene expression test, they were found to have alterations in a part of the DNA responsible for tumor suppression. The genes, called CDKN2A/2B are responsible for triggering cell production of enzymes that normally help prevent cancer. They also found an overabundance of the glycoprotein uromodulin in the mesothelioma cells. These findings suggest that the presence of excess iron put the cells under oxidative stress.
More And Source : http://www.survivingmesothelioma.com/news/view.asp?ID=001048
Sunday, February 13, 2011
20 percent of Mesothelioma Cases Unreported
In a report published Monday, a mesothelioma lawyer in New York said that 20 percent of mesotheliomacases remain unreported.
A recent article in the journal of Environmental Health Perspectives estimated that for every four to five people worldwide who are diagnosed with mesothelioma, at least one case goes unreported. The mesothelioma attorney said even that number undercounts the true death toll of mesothelioma.
In a statement, Joseph W. Belluck said that mesothelioma is a deadly disease that has been underestimated for too long. Mesothelioma is a rare form of cancer, which involves the protective lining that covers several internal body organs such as the pleura, abdomen and the heart. It is commonly caused by excessive exposure to asbestos.
Asbestos, on the other hand, is a naturally occurring mineral that became increasingly popular during the 19th and 20th centuries in a variety of building construction materials for insulation and as a fire-retardant. People who work in industries that mine, make or use asbestos products and those living near these industries commonly develop significant health problems attributed to the exposure.
More and Source : http://www.seedol.com/?p=6932
A recent article in the journal of Environmental Health Perspectives estimated that for every four to five people worldwide who are diagnosed with mesothelioma, at least one case goes unreported. The mesothelioma attorney said even that number undercounts the true death toll of mesothelioma.
In a statement, Joseph W. Belluck said that mesothelioma is a deadly disease that has been underestimated for too long. Mesothelioma is a rare form of cancer, which involves the protective lining that covers several internal body organs such as the pleura, abdomen and the heart. It is commonly caused by excessive exposure to asbestos.
Asbestos, on the other hand, is a naturally occurring mineral that became increasingly popular during the 19th and 20th centuries in a variety of building construction materials for insulation and as a fire-retardant. People who work in industries that mine, make or use asbestos products and those living near these industries commonly develop significant health problems attributed to the exposure.
More and Source : http://www.seedol.com/?p=6932
Mesothelioma risk among power plant workers are high, study says
Mesothelioma was likely to develop among power plant workers who are constantly exposed to large amounts of asbestos, a new study revealed.
Researchers monitored 8,632 power plant workers in Germany who were exposed to asbestos coming from insulation materials used in turbines. Up to 94 percent were exposed for an average duration of 20 to 21 years, the study said.
Asbestos exposure is the main cause of mesothelioma, a rare and deadly type of lung cancer. The substance is used to insulate equipment and wires from the heat generated inside power plants.
Unlike other developed countries, the United States has yet to enforce a complete ban on asbestos despite mounting evidence that it causes many health problems including mesothelioma.
In the study, dust samples taken inside power plants contained chrysotile fibers which are toxic forms of asbestos. When inhaled, the dust causes inflammation which can trigger mesothelioma.
More and Source : http://empowerednews.net/?p=5931
Researchers monitored 8,632 power plant workers in Germany who were exposed to asbestos coming from insulation materials used in turbines. Up to 94 percent were exposed for an average duration of 20 to 21 years, the study said.
Asbestos exposure is the main cause of mesothelioma, a rare and deadly type of lung cancer. The substance is used to insulate equipment and wires from the heat generated inside power plants.
Unlike other developed countries, the United States has yet to enforce a complete ban on asbestos despite mounting evidence that it causes many health problems including mesothelioma.
In the study, dust samples taken inside power plants contained chrysotile fibers which are toxic forms of asbestos. When inhaled, the dust causes inflammation which can trigger mesothelioma.
More and Source : http://empowerednews.net/?p=5931
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